Given the vast health challenges facing Mississippians, the Bower Foundation directs its funds and energies into making sustainable, systemic improvements in the state's health and education infrastructures. Through strong, substantive partnerships with organizations that share its vision, the Foundation leverages limited resources into grants that support mutual goals of better health outcomes and better health policy. Many health policy changes also spur productive grant making.

The legacy of John D. Bower, M.D.'s work inspires the Bower Foundation to be proactive and highly selective in providing grants for the creation, expansion, and support of quality health initiatives.